A selected list of 16 binary protein complexes from the “difficult” and “medium difficult” category of the protein docking benchmark dataset version 4.0 [39].

<p>Each complex has more than 7 predicted (virtual) inter-protein cross-links and was employed to test the impact of cross-links on protein docking calculations. Best models correspond to the models with the shortest mean SAS distance for all 7 cross-links. L-RMSD corresponds to the RMSD value among the smaller protein partners also known as ligands.